China (Mainland)
buy 3 3'-diindolylmethane (dim) at factory price from supplier CAS NO.1968-05-4
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 0 Metric Ton
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
- Available Specifications:
Contact Us(1-9)Metric Ton
- Product Details
Keywords
- 3,3'- Methylenebisindole
- DIM
- at factory price Diindolylmethane
Quick Details
- ProName: buy 3 3'-diindolylmethane (dim) at fac...
- CasNo: 1968-05-4
- Molecular Formula: C17H14N2
- Appearance: powder
- Application: Pharmaceuticals
- ProductionCapacity: Metric Ton/Day
- Purity: Contact Us
- LimitNum: 0 Metric Ton
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Product Description
Diindolylmethane is formed in the body from plant substances contained in “cruciferous” vegetables such as cabbage, Brussels sprouts, cauliflower, and broccoli. Scientists think these vegetables may help to protect the body against cancer because they contain diindolylmethane and a related chemical called indole-3 carbinol. Diindolylmethane is used for preventing breast, uterine, and colorectal cancer. It is also used to prevent an enlarged prostate (benign prostatic hypertrophy, BPH) and treat premenstrual syndrome (PMS).
3,3′-Diindolylmethane ( DIM ) is a compound derived from the digestion of indole-3-carbinol, found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage, and kale.
The reputation of Brassica vegetables as healthy foods rests in part on the activities of diindolylmethane.
Clinical data for the effects of DIM are limited, but because of potential anticancer properties, the National Cancer Institute of the United States has begun clinical trials of DIM as a therapeutic for numerous forms of cancer.
With the function of the anti-tumor agent, the derivative can directly accelerate the apoptosis of human cancer cells and sensitize TRAIL to induce apoptosis of human cancer cells under relatively high concentration conditions, As a new plant growth promoter, the function of DIM and its derivatives has been applied in ecologically friendly systems research.
- DIM induces a G1 cell loop inhibition in human breast cancer MCF-7 cells, by mechanism, and expression;
- DIM is a potent inhibitor of mitochondrial H+-ATPase;
- Prevention of breast cancer, uterine cancer, and colorectal cancer;
- Diindolylmethane is abnormal growth of cells of the cervix (cervical dysplasia);
- Prostate cancer;
- Diindolylmethane can Prevent breast cancer;
- Diindolylmethane can Prevent uterine cancer;
- Diindolylmethane can Prevent colon cancer;
- Diindolylmethane can Prevent prostate enlargement (benign prostatic hypertrophy, BPH);
- Diindolylmethane can Prevent treat premenstrual syndrome (PMS);
- Treat premenstrual conditions.
3,3'-Diindolylmethane is in Phase III clinical trials for Cervical dysplasia, a pre-cancerous condition also caused by the Human Papilloma Virus.At the present time, DIM is used to treat recurrent respiratory papillomatosis (RRP), a rare respiratory disease with tumors in the upper respiratory tracts caused by the human papillomavirus.DIM has been demonstrated to work synergistically with genistein (from soy), in causing apoptotic gene expression in breast cancer cells.
a pharmaceutical intermediate for the production of indole-3-methanol.